Porcine circovirus infection: interaction with the host and its association with disease
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Abstract
Porcine circoviruses (PCVs) are widespread in both domestic and wild pig populations. Four PCV species have been described to date (PCV1 to PCV4), with PCV2 being the most well-documented due to its involvement in porcine circovirus disease. This infection has a complex pathology and presents in different clinical forms, causing significant economic losses for the swine industry. This paper reviews available information on PCVs, including their genotypes, possible associations between disease and the presence of PCV3 and PCV4. The difficulty of establishing this association is discussed, given the high rate of co-infection between PCVs and other pathogenic and emerging viruses.
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