Detección de resistencia en Haemonchus contortus al sulfoxido de albendazol inyectado mediante la prueba de campo de reduccion de huevos en ganado ovino

Abstract

THE OBJECTIVE OF THIS STUDY WAS TO COMPARE THE EFFICACY OF ALBENDAZOLE SULFOXIDE AND LEVAMISOL AGAINST H. CONTORTUS IN SHEEP. ANIMALS WERE GROUPED ACCORDING TO THE HOMOGENEITY OF EGG ELIMINATION. GROUP I (N = 19) WAS TREATED WITH ALBENDAZOLE SULFOXIDE, AND GROUP II (N = 19) WITH LEVAMISOL. BOTH GROUPS WERE INJECTED BY THE RECOMMENDED DOSE INTRAMUSCULARY. GROUP III (N = 18) WITHOUT TREATMENT, WAS CONSIDERED AS THE CONTROL ONE. PERCENTAGE OF EGG REDUCTION ON FECES (PER), CONFIDENCE INTERVAL AT 95% (CI), AND PERCENTAGE OF POSITIVE ANIMALS (PPA) WERE CALCULATED AT SEVEN AND FOURTEEN DAYS AFTER TREATMENT (DAT). AT 7 DAT, GROUP I HAD A PER OF 65.9%, (CI = 44-79%), AND A PPA OF 100%, GROUP II HAD A PER OF 99.7% (CI = 99-100%), AND A PPA OF 15.8%. AT 14 DAT, GROUP I HAD A PER OF 66.2% (CI = 13- 70%), AND A PPA OF 84%; WHEREAS GROUP II HAD A PER OF 100% (CI OF 100%), AND A PPA OF 0%. GROUP III HAD ALWAYS A PPA OF 100%. RESULTS INDICATE THE PRESENCE OF A RESISTANT H. CONTORTUS POPULATION TO ALBENDAZOLE SULFOXIDE. THIS IS THE FIRST REPORT ON THE RESISTANCE OF THIS NEMATODE TO ALBENDAZOLE SULFOXIDE WHICH IS CONSIDERED AS THE FIRST OPTION OF TREATMENT AGAINST THIS PARASITE.